Recommended positive controls: NT2D1, IMR32, U87-MG.
Predicted reactivity: Mouse (90%), Rat (91%), Pig (92%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NOP seven-associated protein 1; WD repeat-containing protein 74
Gene Aliases: NSA1; WDR74
UniProt ID: (Human) Q6RFH5
Entrez Gene ID: (Human) 54663