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Proteintech

WHSC1 Polyclonal Antibody

View all (8) NSD2 antibodies

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WHSC1 Polyclonal Antibody

Product Details

22722-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

WHSC1 Fusion Protein Ag18611 (553-711 aa encoded by BC152412)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.34 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RPKTSTTLS SEEKGKKTKK KTRRRRAKGE GKRQSEDECF RCGDGGQLVL CDRKFCTKAY HLSCLGLGKR PFGKWECPWH HCDVCGKPST SFCHLCPNSF CKEHQDGTAF SCTPDGRSYC CEHDLGAASV RSTKTEKPPP EPGKPKGKRR RRRGWRRVTE (553-711 aa encoded by BC152412)

Target Information

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: contains SET domain; histone methyltransferase; MMSET type III; Histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; MMSET; multiple myeloma SET domain containing protein type III; Multiple myeloma SET domain-containing protein; Nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; Protein trithorax-5; trithorax/ash1-related protein 5; unnamed protein product; Wolf-Hirschhorn syndrome candidate 1; Wolf-Hirschhorn syndrome candidate 1 protein

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Gene Aliases: KIAA1090; KMT3F; KMT3G; MMSET; NSD2; RAUST; REIIBP; TRX5; WHS; WHSC1

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UniProt ID: (Human) O96028

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Entrez Gene ID: (Human) 7468

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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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