The synthetic peptide sequence is 1154-1195aa, DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSED
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Erythrocyte 65 kDa protein; hWNK1; Kinase deficient protein; p65; prostate-derived sterile 20-like kinase; Protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; WNK lysine deficient protein kinase 1 isoform
Gene Aliases: 6430573H23Rik; EG406236; HSAN2; HSN2; KDP; KIAA0344; mKIAA0344; p65; PPP1R167; PRKWNK1; PSK; WNK1