Peptide sequence: WVEDPKKLKG KHKDNEAIEF SFNLETDTPE EVAYEMVKSG FFHESDSKAV
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Members of the 'with no lysine' kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function.
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Protein Aliases: KIAA1566; PRKWNK3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine-protein kinase WNK3; WNK lysine deficient protein kinase 3; WNK lysine deficient protein kinase 3, pseudogene
Gene Aliases: BOS_26021; KIAA1566; PRKWNK3; RGD1563131; WNK3; Wnk3-ps