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WNT10B Polyclonal Antibody

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WNT10B Polyclonal Antibody

Product Details

BS-3662R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human WNT10b, amino acids 201-300.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Protein Wnt-10b; Protein Wnt-12; unnamed protein product; wingless related MMTV integration site 10b; wingless-type MMTV integration site family, member 10B; WNT-10B protein; wnt-12; WNT10B

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Gene Aliases: SHFM6; STHAG8; Wnt-10b; WNT-12; Wnt10; WNT10B; WNT12

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UniProt ID: (Human) O00744, (Mouse) P48614

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Entrez Gene ID: (Human) 7480, (Pig) 100126276, (Rat) 315294, (Mouse) 22410

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Function(s)
receptor binding frizzled binding cytokine activity protein binding receptor agonist activity molecular_function intercellular signal molecule
Process(es)
G2/M transition of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter osteoblast differentiation chondrocyte differentiation regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter lipid metabolic process smoothened signaling pathway cell proliferation positive regulation of G2/M transition of mitotic cell cycle myoblast differentiation involved in skeletal muscle regeneration Wnt signaling pathway neuron differentiation T cell differentiation positive regulation of bone mineralization epithelial cell differentiation positive regulation of epithelial cell differentiation regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of apoptotic process skeletal muscle tissue regeneration cell fate commitment fat cell differentiation positive regulation of T cell differentiation regulation of fat cell differentiation negative regulation of fat cell differentiation positive regulation of osteoblast differentiation positive regulation of ossification positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription from RNA polymerase II promoter animal organ development myoblast development regulation of skeletal muscle tissue development skeletal muscle fiber development negative regulation of epithelial cell proliferation protein stabilization sensory perception of taste regulation of protein metabolic process regulation of cell cycle positive regulation of anagen canonical Wnt signaling pathway bone trabecula formation fungiform papilla development cellular response to retinoic acid cellular response to cAMP cellular response to parathyroid hormone stimulus hematopoietic stem cell proliferation positive regulation of canonical Wnt signaling pathway negative regulation of cold-induced thermogenesis positive regulation of hematopoietic stem cell proliferation cell cycle arrest positive regulation of cell proliferation positive regulation of sequence-specific DNA binding transcription factor activity cellular response to organic substance cellular response to organic cyclic compound cellular response to hydrostatic pressure signal transduction cell-cell signaling multicellular organism development organ morphogenesis
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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