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Invitrogen
WNT10B Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
WNT10B Antibody (PA5-84233)
Relative expression in different tissues in IHC: Detection of differential expression levels of WNT10B demonstrates antibody specificity. Immunohistochemical analysis of WNT10B using anti-WNT10B Polyclonal Antibody (Product #PA5-84233), shows significant staining of WNT10B in cerebral cortex and shows minimal or weak staining in pancreas tissues. The relative expression levels of WNT10B within each tissue ... View More
Product Details
PA5-84233
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human WNT10B. Recombinant protein control fragment (Product #RP-100878).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791385
Product Specific Information
Immunogen sequence: SLGKLVSCGC GWKGSGEQDR LRAKLLQLQA LSRGKSFPHS LPSPGPGSSP SPGPQDTWEW GGCNHDMDFG EKFS
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-10b; Protein Wnt-12; wingless-type MMTV integration site family member 10B; wingless-type MMTV integration site family, member 10B; WNT-10B protein
Gene Aliases: SHFM6; WNT-12; WNT10B; WNT12
UniProt ID: (Human) O00744
Entrez Gene ID: (Human) 7480
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
lipid metabolic process
cell cycle arrest
smoothened signaling pathway
positive regulation of cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
myoblast differentiation involved in skeletal muscle regeneration
Wnt signaling pathway
neuron differentiation
positive regulation of bone mineralization
positive regulation of epithelial cell differentiation
regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
regulation of skeletal muscle tissue development
skeletal muscle fiber development
negative regulation of epithelial cell proliferation
protein stabilization
sensory perception of taste
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of anagen
canonical Wnt signaling pathway
bone trabecula formation
fungiform papilla development
cellular response to retinoic acid
cellular response to cAMP
cellular response to parathyroid hormone stimulus
hematopoietic stem cell proliferation
cellular response to hydrostatic pressure
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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