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Invitrogen
WNT2 Polyclonal Antibody
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Product Details
PA5-78424
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human WNT2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: mouse brain
Predicted Reactivity: Human (100%), Cat (95%), Rabbit (95%), Sheep (92%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (92%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
WNT2 is a ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; Int-1-like protein 1; INT-1-related protein; INT1L 1; IRP; IRP protein; Protein Wnt-2; secreted growth factor; unnamed protein product; wingless-related MMTV integration site 2; wingless-type MMTV integration site family member 2; WNT 2
Gene Aliases: 2610510E18Rik; INT1L1; IRP; Mirp; Wnt-2; WNT2; Wnt2a
UniProt ID: (Human) P09544, (Mouse) P21552
Entrez Gene ID: (Human) 7472, (Mouse) 22413
positive regulation of mesenchymal cell proliferation
lens development in camera-type eye
cell-cell signaling
positive regulation of cell proliferation
mesenchymal cell proliferation
Wnt signaling pathway
neurogenesis
neuron differentiation
cell proliferation in midbrain
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
animal organ development
system development
epithelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of neurogenesis
atrial cardiac muscle tissue morphogenesis
cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
cardiac epithelial to mesenchymal transition
lung induction
positive regulation of epithelial cell proliferation involved in lung morphogenesis
epithelial cell proliferation involved in lung morphogenesis
labyrinthine layer blood vessel development
iris morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
cellular response to transforming growth factor beta stimulus
midbrain dopaminergic neuron differentiation
positive regulation of endothelial cell proliferation
multicellular organism development
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of canonical Wnt signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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