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Proteintech
WNT3 Polyclonal Antibody
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Product Details
28156-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WNT3 fusion protein Ag27965
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Amount
97.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SCAEGTSTIC GCDSHHKGPP GEGWKWGGCS EDADFGVLVS REFADARENR PDARSAMNKH NNEAGRTTIL DHMHLKCKCH GLSGSCEVKT CWWAQPDFRA IGDFLKDKYD SASEMVVEKH RESRGWVETL RAKYSLFKPP TERDLVYYEN SPNFCEPNPE TGSFGTRDRT CNVTSHG
Target Information
WNT3, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4; Proto-oncogene Int-4 homolog; proto-oncogene protein Wnt-3; Proto-oncogene Wnt-3; wingless-related MMTV integration site 3; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
Gene Aliases: Int-4; INT4; TETAMS; Wnt-3; WNT3
UniProt ID: (Human) P56703, (Mouse) P17553
Entrez Gene ID: (Human) 7473, (Mouse) 22415
cell morphogenesis
mesoderm formation
gamete generation
axon guidance
anatomical structure morphogenesis
anterior/posterior axis specification
dorsal/ventral axis specification
anterior/posterior pattern specification
gene expression
positive regulation of gene expression
Wnt signaling pathway
positive regulation of Wnt signaling pathway
neuron differentiation
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cell fate commitment
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
animal organ development
anatomical structure formation involved in morphogenesis
positive regulation of collateral sprouting in absence of injury
system development
negative regulation of axon extension involved in axon guidance
regulation of neurogenesis
Spemann organizer formation at the anterior end of the primitive streak
canonical Wnt signaling pathway
limb development
limb bud formation
head morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
stem cell proliferation
midbrain dopaminergic neuron differentiation
regulation of mesenchymal stem cell differentiation
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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