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Invitrogen
WNT3 Polyclonal Antibody
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FIGURE: 1 / 1
WNT3 Antibody (PA5-78226) in WB
WNT3 Polyclonal Antibody detects WNT3 protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract. B. 30 µg whole cell lysate/extract of Wnt3-transfected 293T cells.10 % SDS-PAGE. WNT3 Polyclonal Antibody (Product # PA5-78226) dilution: 1:5,000.
Product Details
PA5-78226
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human WNT3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Wnt3-transfected 293T cells, Want3A-transfected 293T cells
Predicted Reactivity: Mouse (99%), Rat (99%), Zebrafish (91%), Chicken (98%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
WNT3, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4 homolog; Proto-oncogene Wnt-3; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
Gene Aliases: INT4; TETAMS; WNT3
UniProt ID: (Human) P56703
Entrez Gene ID: (Human) 7473
cell morphogenesis
mesoderm formation
gamete generation
axon guidance
anatomical structure morphogenesis
anterior/posterior axis specification
dorsal/ventral axis specification
anterior/posterior pattern specification
gene expression
positive regulation of gene expression
Wnt signaling pathway
positive regulation of Wnt signaling pathway
neuron differentiation
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cell fate commitment
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
animal organ development
anatomical structure formation involved in morphogenesis
positive regulation of collateral sprouting in absence of injury
system development
negative regulation of axon extension involved in axon guidance
regulation of neurogenesis
Spemann organizer formation at the anterior end of the primitive streak
canonical Wnt signaling pathway
limb development
limb bud formation
head morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
stem cell proliferation
midbrain dopaminergic neuron differentiation
regulation of mesenchymal stem cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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