Positive Control: human WNT3A-transfected 293T cells
Predicted Reactivity: Mouse (98%), Rat (98%), Zebrafish (87%), Xenopus laevis (86%), Chicken (87%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Wnt3a, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC119418; MGC119419; MGC119420; Protein Wnt-3a; wingless-related MMTV integration site 3A; wingless-type MMTV integration site family member 3A; wingless-type MMTV integration site family, member 3A; Wnt 3a; WNT3A protein
Gene Aliases: WNT3A
UniProt ID: (Human) P56704
Molecular Function: intercellular signal molecule