Human Wnt5a shares 100% amino acid (aa) sequences identity with both mouse and rat Wnt5a.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.
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Protein Aliases: OTTHUMP00000212837; OTTHUMP00000212861; Protein Wnt-5a; wingless-related MMTV integration site 5A; wingless-type MMTV integration site 5A; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein
Gene Aliases: 8030457G12Rik; hWNT5A; Wnt-5a; WNT5A
Molecular Function: intercellular signal molecule