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Invitrogen
WNT5B Polyclonal Antibody
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Product Details
PA5-33115
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from internal region of human WNT5B.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey (100%); Gorilla, Marmoset (93%); Dog, Elephant, Horse, Rabbit, Opossum (86%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-5b; unnamed protein product; wingless-type MMTV integration site family, member 5B; WNT-5B protein
Gene Aliases: WNT5B
UniProt ID: (Human) Q9H1J7
Entrez Gene ID: (Human) 81029
chondrocyte differentiation
Wnt signaling pathway
neuron differentiation
positive regulation of cell migration
muscle cell differentiation
cell fate commitment
fat cell differentiation
positive regulation of fat cell differentiation
canonical Wnt signaling pathway
lens fiber cell development
cellular response to retinoic acid
negative regulation of canonical Wnt signaling pathway
positive regulation of convergent extension involved in gastrulation
positive regulation of non-canonical Wnt signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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