PA5-28289 targets WNT7A in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28289 immunogen is recombinant protein fragment corresponding to a region within amino acids 20 and 349 of Human WNT7A.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
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Protein Aliases: Protein Wnt-7a; proto-oncogene Wnt7a protein; wingless-type MMTV integration site family member 7A; wingless-type MMTV integration site family, member 7A
Gene Aliases: WNT7A
UniProt ID: (Human) O00755
Entrez Gene ID: (Human) 7476
Molecular Function: signaling molecule