Recommended positive controls: NT2D1, mouse bladder, 293T transfected recombinant WNT7B protein, V5-human Wnt7b-transfected 293T.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (87%), Chicken (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Wnt7b encodes a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein.
Protein Aliases: Protein Wnt-7b; wingless-related MMTV integration site 7B; wingless-type MMTV integration site family member 7B; wingless-type MMTV integration site family, member 7B
Gene Aliases: Wnt-7b; WNT7B
Molecular Function: signaling molecule