Positive Control: human Wnt8A-transfected 293T cells
Predicted Reactivity: Mouse (80%), Rat (82%), Bovine (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
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Protein Aliases: member 8A; Protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family; wingless-type MMTV integration site family member 8A; wingless-type MMTV integration site family, member 8A; WNT8A; WNT8D
Gene Aliases: WNT8A; WNT8D
UniProt ID: (Human) Q9H1J5
Entrez Gene ID: (Human) 7478
Molecular Function: signaling molecule