In Western blots, less than 5% cross-reactivity with recombinant human (rh) Wnt-2, rhWnt-9a, recombinant mouse (rm) Wnt-1, rmWnt-2b, rmWnt-3a, rmWnt-4, rmWnt-5a, rmWnt-5b, rmWnt-11, and rmWnt-16 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
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Protein Aliases: Protein Wnt-14b; Protein Wnt-15; Protein Wnt-9b; wingless-type MMTV integration site 15; wingless-type MMTV integration site 9B; wingless-type MMTV integration site family, member 15; WNT14B; WNT15; WNT9B
Gene Aliases: clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15; Wnt9b
UniProt ID: (Mouse) O35468
Entrez Gene ID: (Mouse) 22412
Molecular Function: signaling molecule