This target displays homology in the following species: Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%; Yeast: 83%
This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
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Protein Aliases: BH-3-only member B; BH3-only member B protein; Protein WWC2; WW domain-containing protein 2; WW, C2 and coiled-coil domain containing 2
Gene Aliases: 5330431C14Rik; AU022508; BOMB; C85457; D8Ertd594e; MNCb-4173; RGD1559427; WWC2