Bioss

Wnt3a Polyclonal Antibody

View all (14) WNT3A antibodies

Questions & Answers

Questions & Answers

Questions & Answers

Additional Information:

{{banner.description}}

{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

Antibody Testing Data (1)

Wnt3a Antibody in Western Blot (WB)

Wnt3a Antibody in Western Blot (WB)

FIGURE: 1 / 1

Wnt3a Antibody (BS-23278R) in WB

Lane 1:Rat Cerebrum tissue lysates; Lane 2: Rat Stomach tissue lysates probed with Wnt3a Polyclonal Antibody, Unconjugated (bs-23278R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.

Wnt3a Antibody in Western Blot (WB)

Product Image Gallery

Wnt3a Antibody in Western Blot (WB) — Lane 1:Rat Cerebrum tissue lysates; Lane 2: Rat Stomach tissue lysates probed with Wnt3a Polyclonal Antibody, Unconjugated (bs-23278R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.

Product Details

BS-23278R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:5,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Wnt3a

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

100 µg

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.03% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Wnt3a, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-related MMTV integration site 3A; Wnt 3a; WNT3A protein

View more View less

Entrez Gene ID: (Rat) 303181

View more View less

molecular_function transcription coactivator activity frizzled binding frizzled-2 binding protein domain specific binding receptor agonist activity intercellular signal molecule

osteoblast differentiation in utero embryonic development somitogenesis positive regulation of cytokine production positive regulation of protein phosphorylation heart looping positive regulation of receptor internalization negative regulation of heart induction by canonical Wnt signaling pathway determination of left/right symmetry axonogenesis axon guidance mesoderm development biological_process positive regulation of cell proliferation anterior/posterior pattern specification COP9 signalosome assembly negative regulation of neuron projection development Wnt signaling pathway spinal cord association neuron differentiation hippocampus development cell proliferation in forebrain Wnt signaling pathway involved in forebrain neuroblast division dorsal/ventral neural tube patterning hemopoiesis platelet activation neuron differentiation extracellular matrix organization mammary gland development positive regulation of B cell proliferation positive regulation of protein binding positive regulation of peptidyl-serine phosphorylation cellular protein localization positive regulation of catenin import into nucleus skeletal muscle cell differentiation post-anal tail morphogenesis inner ear morphogenesis positive regulation of cysteine-type endopeptidase activity involved in apoptotic process cell fate commitment regulation of cell differentiation negative regulation of fat cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter somatic stem cell division positive regulation of mesodermal cell fate specification paraxial mesodermal cell fate commitment positive regulation of collateral sprouting in absence of injury negative regulation of axon extension involved in axon guidance negative regulation of neurogenesis regulation of axonogenesis positive regulation of sequence-specific DNA binding transcription factor activity palate development canonical Wnt signaling pathway cardiac muscle cell fate commitment positive regulation of protein tyrosine kinase activity positive regulation of dermatome development canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment regulation of microtubule cytoskeleton organization platelet aggregation axis elongation involved in somitogenesis positive regulation of canonical Wnt signaling pathway positive regulation of cell-cell adhesion mediated by cadherin positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation positive regulation of neural precursor cell proliferation positive regulation of cardiac muscle cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support