Invitrogen

XIAP Polyclonal Antibody

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XIAP Polyclonal Antibody

Product Details

PA5-93254

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 198-497 of human XIAP (NP_0011582)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.58 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2806694

Product Specific Information

Immunogen sequence: VQCFCCGGKL KNWEPCDRAW SEHRRHFPNC FFVLGRNLNI RSESDAVSSD RNFPNSTNLP RNPSMADYEA RIFTFGTWIY SVNKEQLARA GFYALGEGDK VKCFHCGGGL TDWKPSEDPW EQHAKWYPGC KYLLEQKGQE YINNIHLTHS LEECLVRTTE KTPSLTRRID DTIFQNPMVQ EAIRMGFSFK DIKKIMEEKI QISGSNYKSL EVLVADLVNA QKDSMQDESS QTSLQKEIST EEQLRRLQEE KLCKICMDRN IAIVFVPCGH LVTCKQCAEA VDKCPMCYTV ITFKQKIFMS

Positive Samples: MCF-7, HeLa, SW620, HepG2, Jurkat, Mouse liver, Rat kidney; Cellular Location: Cytoplasm, Nucleus

Target Information

ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: apoptosis inhibitor protein 3; baculoviral IAP repeat-containing 4; Baculoviral IAP repeat-containing protein 4; BIR4; E3 ubiquitin-protein ligase XIAP; HILP; IAP homolog A; IAP-3; IAP-like protein; ILP; Inhibitor of apoptosis protein 3; RIAP-3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

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Gene Aliases: 1110015C02Rik; Aipa; API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP-1; ILP1; MIHA; riap3; XIAP; XLP2

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UniProt ID: (Human) P98170, (Rat) Q9R0I6, (Mouse) Q60989

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Entrez Gene ID: (Human) 331, (Rat) 63879, (Mouse) 11798

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Function(s)
ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process ubiquitin protein ligase activity protease binding scaffold protein binding UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity protease inhibitor
Process(es)
apoptotic process cellular response to DNA damage stimulus Wnt signaling pathway protein ubiquitination regulation of BMP signaling pathway positive regulation of protein ubiquitination regulation of cell proliferation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of innate immune response regulation of inflammatory response copper ion homeostasis regulation of nucleotide-binding oligomerization domain containing signaling pathway positive regulation of canonical Wnt signaling pathway mitotic spindle assembly positive regulation of protein linear polyubiquitination inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process neuron apoptotic process
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