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Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
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Protein Aliases: hXkr8; RP11-460I13.3; X Kell blood group precursor-related family, member 8; X-linked Kx blood group related 8; XK, Kell blood group complex subunit-related family, member 8; XK-related protein 8
Gene Aliases: hXkr8; XKR8; XRG8
UniProt ID: (Human) Q9H6D3
Entrez Gene ID: (Human) 55113
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