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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide corresponding to the carboxy-terminus of human XPB.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23344 detects XPB, CT in Human samples.
PA1-23344 has been successfully used in Western Blot procedures.
PA1-23344 immunogen corresponds to Peptide corresponding to the carboxy-terminus of human XPB..
The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne's syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
basic transcription factor 2 89 kDa subunit; BTF2; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair helicase; DNA repair protein complementing XP-B cells; excision repair cross-complementation group 3; excision repair cross-complementing rodent repair deficiency, complementation group 3; GTF2H; RAD25; TFIIH; TFIIH 89 kDa subunit; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH p89; xeroderma pigmentosum group B-complementing protein; xeroderma pigmentosum, complementation group B; XPB
BTF2; ERCC3; GTF2H; RAD25; TFIIH; TTD2; XPB; XPBC