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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human XPB.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with fruit fly (Drosophila melanogaster), zebrafish and cynomolgus monkey based on sequence homology.
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 and thus functions in class II transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
basic transcription factor 2 89 kDa subunit; BTF2 p89; BTF2, GTF2H, RAD25, TFIIH, XPB, BTF2 p89; BTF2-p89; DNA excision repair protein ERCC-3; DNA repair helicase; DNA repair protein complementing XP-B cells; excision repair 3; excision repair cross-complementation group 3; excision repair cross-complementing rodent repair deficiency, complementation group 3; TFIIH 89 kDa subunit; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH p89; xeroderma pigmentosum group B-complementing protein; xeroderma pigmentosum, complementation group B
BTF2; BTF2 p89; Ercc-3; ERCC3; GTF2H; RAD25; TFIIH; TTD2; XPB; XPBC