Immunogen sequence: MRLSQKWQVI NQRSLLCGED EAADENPESQ EMLEEQLVRM LTREVMDLIT VCCVSKKGAD HSSAPPADGD DEEMMATEVT PSAMAELTDL GKCLMKHEDV CTALLITAFN SLAWKDTLSC QRTTSQLCWP LLKQVLSGTL LADAVTWLFT SVLKGLQMHG QHDGCMASLV HLAFQIYEAL RPRYLEIRAV MEQIPEIQKD SLDQFDCKLL NPSLQKVADK RRKDQFKRLI AGCIGKPLGE QFRKEVHIKN LPSLFKKTKP MLETEVLDND GGGLATIFEP; Positive Samples: MCF7, U-251MG, NIH/3T3, HeLa, PC-12, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Nucleus
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.
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Protein Aliases: Exp5; Exportin-5; Ran-binding protein 21
Gene Aliases: 2410004H11Rik; 2700038C24Rik; AI648907; AW549301; Exp5; KIAA1291; mKIAA1291; RANBP21; XPO5
Molecular Function: receptor