Proteintech

XPR1 Polyclonal Antibody

View all (6) XPR1 antibodies

Questions & Answers

Questions & Answers

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XPR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human heart using 14174-1-AP (XPR1 antibody) at dilution of 1:100 (under 40x lens).

XPR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human heart using 14174-1-AP (XPR1 antibody) at dilution of 1:100 (under 10x lens).

XPR1 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 14174-1-AP (XPR1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

XPR1 Antibody in Flow Cytometry (Flow) — 1X10^6 Jurkat cells were stained with 0.2ug XPR1 antibody (14174-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L) with dilution 1:1000.

Product Details

14174-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Flow Cytometry (Flow)	0.2 µg/1x10^6 cells	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	XPR1 Fusion Protein Ag5373 (1-234 aa encoded by BC041142) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.15 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MKFAEHLSA HITPEWRKQY IQYEAFKDML YSAQDQAPSV EVTDEDTVKR YFAKFEEKFF QTCEKELAKI NTFYSEKLAE AQRRFATLQN ELQSSLDAQK ESTGVTTLRQ RRKPVFHLSH EERVQHRNIK DLKLAFSEFY LSLILLQNYQ NLNFTGFRKI LKKHDKILET SRGADWRVAH VEVAPFYTCK KINQLISETE AVVTNELEDG DRQKAMKRLR VPPLGAAQPA PAWTT (1-234 aa encoded by BC041142)

Target Information

Xenotropic and polytropic retrovirus receptor (XPR1) is an Orphan-U GPCR with an unknown ligand. ESTs have been isolated from brain, breast, kidney, pancreas, placenta, prostate, skeletal muscle, testis, and tonsil libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Protein SYG1 homolog; receptor for MCF virus 1; Rmc-1; RP11-46A10.1; suppressor of yeast G deletion; susceptibility to xenotropic virus; X-receptor; xenotropic and polytropic murine leukemia virus receptor; Xenotropic and polytropic murine leukemia virus receptor X3; Xenotropic and polytropic retrovirus receptor 1; xenotropic and polytropic retrovirus receptor 1 homolog

Gene Aliases: IBGC6; Rmc-1; Rmc1; Sxv; SYG1; X3; XPR1; XR

UniProt ID: (Human) Q9UBH6, (Mouse) Q9Z0U0

Entrez Gene ID: (Human) 9213, (Mouse) 19775, (Rat) 289424

Molecular Function: secondary carrier transporter

G-protein coupled receptor signaling pathway response to virus cellular phosphate ion homeostasis phosphate ion transmembrane transport viral entry into host cell

Process(es)

inositol hexakisphosphate binding virus receptor activity receptor activity transmembrane signaling receptor activity G-protein coupled receptor activity phosphate ion transmembrane transporter activity efflux transmembrane transporter activity