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Proteintech
XRN1 Polyclonal Antibody
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Product Details
23108-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
XRN1 Fusion Protein Ag19398 (222-576 aa encoded by BC078146)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to the XRN1 protein.
Immunogen sequence: SLLREEVRF GGKKTQRVCA PEETTFHLLH LSLMREYIDY EFSVLKEKIT FKYDIERIID DWILMGFLVG NDFIPHLPHL HINHDALPLL YGTYVTILPE LGGYINESGH LNLPRFEKYL VKLSDFDREH FSEVFVDLKW FESKVGNKYL NEAAGVAAEE ARNYKEKKKL KGQENSLCWT ALDKNEGEMI TSKDNLEDET EDDDLFETEF RQYKRTYYMT KMGVDVVSDD FLADQAACYV QAIQWILHYY YHGVQSWSWY YPYHYAPFLS DIHNISTLKI HFELGKPFKP FEQLLAVLPA ASKNLLPACY QHLMTNEDSP IIEYYPPDFK TDLNGKQQEW EAVVLIPFID EKRLLE (222-576 aa encoded by BC078146)
Target Information
SEC24C is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-Sep; 5'-3' exoribonuclease 1; DKFZp434P0721; DKFZp686B22225; DKFZp686F19113; FLJ41903; microtubule-associated; GDNF-inducible; protein Dhm2; Strand-exchange protein 1 homolog; unnamed protein product
Gene Aliases: Dhm2; exo; mXrn1; SEP1; XRN1
UniProt ID: (Human) Q8IZH2
Entrez Gene ID: (Human) 54464, (Mouse) 24127
G-quadruplex RNA binding
nucleic acid binding
DNA binding
RNA binding
nuclease activity
exonuclease activity
5'-3' exoribonuclease activity
protein binding
5'-3' exonuclease activity
hydrolase activity
G-quadruplex DNA binding
telomerase RNA binding
3'-5'-exoribonuclease activity
poly(A) RNA binding
exoribonuclease
nuclear-transcribed mRNA catabolic process
RNA metabolic process
rRNA catabolic process
negative regulation of translation
negative regulation of telomere maintenance via telomerase
response to testosterone
nuclear mRNA surveillance
histone mRNA catabolic process
cellular response to cycloheximide
cellular response to puromycin
telomere maintenance
RNA processing
meiotic nuclear division
cell aging
RNA phosphodiester bond hydrolysis, exonucleolytic
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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