Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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PA1-31180 detects XTP4 from human samples.
PA1-31180 has been successfully used in Western blot applications.
The PA1-31180 immunogen is: Synthetic peptide: SNGETLEKITNSRPPC, corresponding to C terminal amino acids 97-112 of Human XTP4.
During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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