Recommended positive controls: 293T, Raji.
Predicted reactivity: Chicken (86%), Rhesus Monkey (86%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC41856; YY1-associated factor 2
Gene Aliases: YAF2
UniProt ID: (Human) Q8IY57
Entrez Gene ID: (Human) 10138