This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: AFKCMMCDVR KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK NSHKKTRPRL KNVDRSSAQH LEVTVGDLTV IITDFKEKTK SPPASSAASA DQHSQSGSSS DNTERGMSRS SS
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC41856; YY1-associated factor 2
Gene Aliases: YAF2
UniProt ID: (Human) Q8IY57
Entrez Gene ID: (Human) 10138