Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SKEYTLDVYR LSSVVTQHDS KKAGAEVVKQ VEHPLLSGLL YPGLQALDEE YLKVDAQFGG IDQRKIFTFA EKYLPALGYS KRVHLMNPMV PGLTGSKMSS SEEESKIDLL DRKEDVKK
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: tyrosine tRNA ligase 1, cytoplasmic; Tyrosine--tRNA ligase, cytoplasmic; tyrosyl trna synthetase; tyrosyl--tRNA ligase; Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase, cytoplasmic; TyrRS
Gene Aliases: CMTDIC; TYRRS; YARS; YARS1; YRS; YTS
UniProt ID: (Human) P54577
Entrez Gene ID: (Human) 8565
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support