Search
Fabgennix
YES1 Polyclonal Antibody, FITC
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
YES1-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 450-480 on human YES1 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: c-Src; cellular yes-1 protein; EC 2.7.10.2; p60-Src; p61-Yes; pp60c-src; Proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; Tyrosine-protein kinase Yes; unnamed protein product; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; viral oncogene yes homolog; Yamagichi sarcoma viral (v-yes-1) oncogene homolog 1; Yamaguchi sarcoma oncogene; Yamaguchi sarcoma viral oncogene homolog 1; YES1 proto-oncogene, Src family tyrosine kinase
Gene Aliases: c-Yes; HsT441; p60c-yes; P61-YES; YES; YES1
UniProt ID: (Human) P07947, (Mouse) Q04736
Entrez Gene ID: (Human) 7525, (Rat) 24884, (Mouse) 22612
nucleotide binding
phosphotyrosine binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
kinase activity
transferase activity
enzyme binding
ion channel binding
epidermal growth factor receptor binding
transferase activity, transferring phosphorus-containing groups
transmembrane receptor protein tyrosine kinase signaling pathway
glucose transport
peptidyl-tyrosine phosphorylation
cell differentiation
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
cellular response to retinoic acid
cellular response to peptide hormone stimulus
cellular response to transforming growth factor beta stimulus
negative regulation of inflammatory response to antigenic stimulus
regulation of glucose transport
T cell costimulation
protein modification process
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of vascular permeability
ephrin receptor signaling pathway
leukocyte migration
protein phosphorylation
phosphorylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support