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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human YLAT2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This protein involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. It requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. It also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. It plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It involved in the transport of L-arginine in monocytes and reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
amino acid permease; cationic amino acid transporter; cationic amino acid transporter, y+ system; LAT-2; LAT3; member 6; SLC7A6; solute carrier family 7 (amino acid transporter light chain, y+L system), member 6; solute carrier family 7 (cationic amino acid transporter; solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; y+ system; y+ system); y+LAT-2; y+LAT2
KIAA0245; LAT-2; LAT3; SLC7A6; y+LAT-2