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Proteintech
YME1L1 Polyclonal Antibody
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Product Details
11510-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
YME1L1 Fusion Protein Ag2069 (348-716 aa encoded by BC023507)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GSEFDEMFV GVGASRIRNL FREAKANAPC VIFIDELDSV GGKRIESPMH PYSRQTINQL LAEMDGFKPN EGVIIIGATN FPEALDNALI RPGRFDMQVT VPRPDVKGRT EILKWYLNKI KFDQSVDPEI IARGTVGFSG AELENLVNQA ALKAAVDGKE MVTMKELEFS KDKILMGPER RSVEIDNKNK TITAYHESGH AIIAYYTKDA MPINKATIMP RGPTLGHVSL LPENDRWNET RAQLLAQMDV SMGGRVAEEL IFGTDHITTG ASSDFDNATK IAKRMVTKFG MSEKLGVMTY SDTGKLSPET QSAIEQEIRI LLRDSYERAK HILKTHAKEH KNLAEALLTY ETLDAKEIQI VLEGKKLEVR (348-716 aa encoded by BC023507)
Target Information
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent metalloprotease YME1L1; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; unnamed protein product; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; OPA11; PAMP; UNQ1868/PRO4304; YME1L; YME1L1
UniProt ID: (Human) Q96TA2, (Mouse) O88967
Entrez Gene ID: (Human) 10730, (Rat) 114217, (Mouse) 27377
proteolysis
misfolded or incompletely synthesized protein catabolic process
mitochondrion organization
cell proliferation
cellular response to starvation
positive regulation of mitochondrial fusion
protein hexamerization
mitochondrial protein processing
mitochondrial protein catabolic process
negative regulation of apoptotic process
neuronal stem cell population maintenance
regulation of stem cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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