YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
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Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent metalloprotease YME1L1; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; PAMP; UNQ1868/PRO4304; YME1L; YME1L1