Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (IHC) |
1:500-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
0.25-2 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human YME1L1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2649732 |
Immunogen sequence: AVDGKEMVTM KELEFSKDKI LMGPERRSVE IDNKNKTITA YHESGHAIIA YYTKDAMPIN KATIMPRGPT LGHVSLLPEN DRWNETRAQL LAQMDVS
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; PAMP; UNQ1868/PRO4304; YME1L; YME1L1
UniProt ID: (Human) Q96TA2
Entrez Gene ID: (Human) 10730
Molecular Function:
immunoglobulin
metalloprotease
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