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Product Details
15403-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
YPEL3 Fusion Protein Ag7626 (1-119 aa encoded by BC005009) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Storage conditions |
-20°C |
Product Specific Information
15403-1-AP was raised against full length of YPEL3 protein (1-119 aa); it can recognize YPEL1-4.
Immunogen sequence: MVRISKPKT FQAYLDDCHR RYSCAHCRAH LANHDDLISK SFQGSQGRAY LFNSVVNVGC GPAEERVLLT GLHAVADIHC ENCKTTLGWK YEQAFESSQK YKEGKYIIEL NHMIKDNGWD (1-119 aa encoded by BC005009)
Target Information
YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein yippee-like 3; Small ubiquitinated apoptotic protein; yippee-like 3
Gene Aliases: FKSG5; Suap; YPEL3
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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