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          • Primary Antibodies ›
          • YTHDC2 Antibodies

          Bethyl Laboratories

          YTHDC2 Polyclonal Antibody

          View all (13) YTHDC2 antibodies

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          Cite YTHDC2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          YTHDC2 Antibody in Western Blot (WB)
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          YTHDC2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          YTHDC2 Antibody (A303-025A) in WB

          Detection of human YTHDC2 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-YTHDC2 antibody (Product # A303-025A) used for WB at 0.04 µg/mL (A) and 0.4 µg/mL (B) and used for IP at 6 µg/mg lysate. YTHDC2 was also immunoprecipitated by rabbit anti-YTHDC2 antibody A303-026A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 se... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          YTHDC2 Antibody in Western Blot (WB)
          YTHDC2 Polyclonal Antibody

          Product Details

          A303-025A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunoprecipitation (IP)

          2-5 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1200 and 1250 of Human YTH Domain Containing 2.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.20 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.0 to 8.0, with 0.1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Based on 100% sequence identity, this antibody is predicted to react with Orangutan

          Target Information

          Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: 3'-5' RNA helicase YTHDC2; CsA-associated helicase-like protein; DKFZp564A186; FLJ10053; FLJ2194; hYTHDC2; probable ATP-dependent RNA helicase YTHDC2; unnamed protein product; YTH domain containing 2; YTH domain-containing protein 2

          View more View less

          Gene Aliases: CAHL; hYTHDC2; YTHDC2

          View more View less

          UniProt ID: (Human) Q9H6S0

          View more View less

          Entrez Gene ID: (Human) 64848

          View more View less

          Function(s)
          nucleotide binding nucleic acid binding RNA binding RNA helicase activity helicase activity protein binding ATP binding RNA-dependent ATPase activity hydrolase activity ATPase activity 3'-5' RNA helicase activity RNA polymerase binding N6-methyladenosine-containing RNA binding
          Process(es)
          spermatogenesis spermatid development cell differentiation response to tumor necrosis factor positive regulation by host of viral genome replication oogenesis oocyte development meiotic cell cycle germline cell cycle switching, mitotic to meiotic cell cycle response to interleukin-1
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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