Proteintech

YWHAH Polyclonal Antibody

Product Image Gallery

YWHAH Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of Hela cells, using YWHAH antibody 15222-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

YWHAH Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 15222-1-AP (YWHAH antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

YWHAH Antibody in Immunoprecipitation (IP) — IP result of anti-YWHAH (IP:15222-1-AP, 4ug; Detection:15222-1-AP 1:1000) with NIH/3T3 cells lysate 1600ug.

Product Details

15222-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 2 publications 2 publications
Immunocytochemistry (ICC/IF)	1:10-1:100	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	YWHAH Fusion Protein Ag7435 (1-246 aa encoded by BC003047) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.18 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

This antibody was raised against the full-length YWHAH.

Immunogen sequence: MGDREQLLQ RARLAEQAER YDDMASAMKA VTELNEPLSN EDRNLLSVAY KNVVGARRSS WRVISSIEQK TMADGNEKKL EKVKAYREKI EKELETVCND VLSLLDKFLI KNCNDFQYES KVFYLKMKGD YYRYLAEVAS GEKKNSVVEA SEAAYKEAFE ISKEQMQPTH PIRLGLALNF SVFYYEIQNA PEQACLLAKQ AFDDAIAELD TLNEDSYKDS TLIMQLLRDN LTLWTSDQQD EEAGEGN (1-246 aa encoded by BC003047)

Target Information

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.

Journal of experimental & clinical cancer research : CR

Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B

Thu Jan 03 00:00:00 EST 2019

14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.

Journal of experimental & clinical cancer research : CR

Song J,Zhang X,Liao Z,Liang H,Chu L,Dong W,Zhang X,Ge Q,Liu Q,Fan P,Zhang Z,Zhang B

Thu Jan 03 00:00:00 EST 2019

Capsaicin prevents mitochondrial damage, protects cardiomyocytes subjected to anoxia/reoxygenation injury mediated by 14-3-3η/Bcl-2.

European journal of pharmacology

Huang J,Liu Z,Xu P,Zhang Z,Yin D,Liu J,He H,He M

Mon Jan 15 00:00:00 EST 2018

Bioinformatics

Protein Aliases: 14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 1433F; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA114-3-3 eta

Gene Aliases: 14-3-3e; YWHA1; YWHAH

UniProt ID: (Human) Q04917, (Rat) P68511, (Mouse) P68510

Entrez Gene ID: (Human) 7533, (Rat) 25576, (Mouse) 22629

Molecular Function: scaffold/adaptor protein