|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 339-384 of human ZC3H11A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 89 kDa.
Purity is >95% by SDS-PAGE.
ZC3H11A (zinc finger CCCH domain-containing protein 11A), also known as KIAA0663 or ZC3HDC11A, is an 810 amino acid protein that contains 3 C3 H1-type zinc fingers. ZC3H11A is expressed in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, fetal brain and fetal liver. The gene encoding ZC3H11A maps to human chromosome 1q32.1 and mouse chromosome 1 E4. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene on chromosome 1 which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.