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Rockland
ZC3H12D Polyclonal Antibody
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FIGURE: 1 / 1
ZC3H12D Antibody (600-401-GC7) in WB
Western Blot of ZC3H12D antibody. Lane 1: THP-1 cell lysate in the absence of blocking peptide. Lane 2: THP-1 cell lysate in the presence of blocking peptide. Primary Antibody: Anti-ZC3H12D antibody at 1 µg/mL. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 58 kDa, 94 kDa for ZC3H12D. Other band(s): ZC3H12D splice variants and isoforms.
Product Details
600-401-GC7
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-ZC3H12D antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human ZC3H12D.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MCP-induced protein 4; p34; Probable ribonuclease ZC3H12D; RP1-281H8.5; Transformed follicular lymphoma; tumor suppressor TFL; Zinc finger CCCH domain-containing protein 12D
Gene Aliases: C6orf95; dJ281H8.1; MCPIP4; p34; TFL; ZC3H12D
UniProt ID: (Human) A2A288
Entrez Gene ID: (Human) 340152
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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