Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human ZC3H8(Accession Q8N5P1), corresponding to amino acid residues I98-K126. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol, 150mM NaCl |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2851394 |
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fetal liver zinc finger 1; fetal liver zinc finger 1; putative zinc finger protein FLIZ1; Fetal liver zinc finger protein 1; Zinc finger CCCH domain-containing protein 8; zinc finger CCCH type domain containing 8; zinc finger CCCH-type domain containing 8
Gene Aliases: AU020882; E130108N08Rik; Fliz1; ZC3H8; ZC3HDC8
UniProt ID: (Human) Q8N5P1, (Mouse) Q9JJ48
Entrez Gene ID: (Human) 84524, (Mouse) 57432
Molecular Function:
zinc finger transcription factor
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