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ZCRB1 Polyclonal Antibody
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FIGURE: 1 / 1
ZCRB1 Antibody (600-401-GC9) in WB
Western Blot of ZCRB1 antibody. Lane 1: Raji cell lysate with ZCRB1 antibody at 1 µg/mL. Lane 2: Raji cell lysate with ZCRB1 antibody at 2 µg/mL. Load: 35 µg per lane. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 25 kDa, 20 kDa for ZCRB1. Other band(s): ZCRB1 splice variants and isoforms.
Product Details
600-401-GC9
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-ZCRB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human ZCRB1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MADP-1; MGC26805; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; zinc finger CCHC-type and RNA binding motif 1; Zinc finger CCHC-type and RNA-binding motif-containing protein 1
Gene Aliases: 2700088M22Rik; MADP-1; MADP1; RBM36; RGD1309851; SNRNP31; ZCCHC19; ZCRB1
UniProt ID: (Human) Q8TBF4, (Rat) Q499V6, (Mouse) Q9CZ96
Entrez Gene ID: (Human) 85437, (Rat) 362990, (Mouse) 67197
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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