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ZDHHC8 Polyclonal Antibody
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FIGURE: 1 / 1
ZDHHC8 Antibody (BS-18486R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with ZDHHC8/ZNF378 Polyclonal Antibody, Unconjugated (bs-18486R) at 1:500 overnight at 4°C, DAB staining.
Product Details
BS-18486R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ZDHHC8/ZNF378, amino acids 561-765.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DHHC-8; DHHC-containing protein 8; Em:AC006547.5; membrane-associated DHHC8 zinc finger protein; Palmitoyltransferase ZDHHC8; probable palmitoyltransferase ZDHHC8; unnamed protein product; Zinc finger DHHC domain-containing protein 8; zinc finger DHHC-type containing 8; zinc finger DHHC-type palmitoyltransferase 8; Zinc finger protein 378; zinc finger, DHHC domain containing 8; zinc finger, DHHC domain like containing 1; zinc finger, DHHC-type containing 8-like
Gene Aliases: D16H22S1738E; DHHC-8; DHHC8; E330009O14Rik; KIAA1292; Op53c05; ZDHHC8; ZDHHCL1; ZNF378
UniProt ID: (Human) Q9ULC8, (Mouse) Q5Y5T5
Entrez Gene ID: (Human) 29801, (Rat) 303796, (Mouse) 27801
locomotory behavior
protein palmitoylation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
positive regulation of cholesterol efflux
peptidyl-L-cysteine S-palmitoylation
high-density lipoprotein particle assembly
positive regulation by host of viral process
regulation of postsynapse assembly
positive regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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