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Immunofluorescent analysis of ZFAT showing staining in the nucleus of SKNSH cells. SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a ZFAT polyclonal antibody (Product # PA5-32037) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10µm.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 825 and 1083 of Human ZFAT|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-32037 targets ZFAT in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-32037 immunogen is recombinant fragment corresponding to a region within amino acids 825 and 1083 of Human ZFAT.
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AITD3; ZFAT1; zinc finger and AT hook domain containing; zinc finger gene in autoimmune thyroid disease; zinc finger protein 406; zinc finger protein ZFAT; zinc-finger gene in AITD susceptibility region; ZNF406
AITD3; KIAA1485; ZFAT; ZFAT1; ZNF406