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Invitrogen
ZFAT Polyclonal Antibody
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FIGURE: 1 / 4
ZFAT Antibody (PA5-32037) in ICC/IF
ZFAT Polyclonal Antibody detects ZFAT protein at nucleus by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ZFAT protein stained by ZFAT Polyclonal Antibody (Product # PA5-32037) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
PA5-32037
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ZFAT. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Jurkat, Raji.
Predicted reactivity: Mouse (97%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ZFAT zinc finger 1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; zinc finger protein 403; Zinc finger protein 406; Zinc finger protein ZFAT; zinc-finger gene in AITD susceptibility region
Gene Aliases: AITD3; Gm922; KIAA1485; ZFAT; ZFAT1; Zfp406; ZNF406
UniProt ID: (Human) Q9P243, (Mouse) Q7TS63
Entrez Gene ID: (Human) 57623, (Mouse) 380993
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
nucleic acid binding
DNA binding
C2H2 zinc finger transcription factor
hematopoietic progenitor cell differentiation
transcription from RNA polymerase II promoter
multicellular organism development
positive regulation of transcription from RNA polymerase II promoter
spongiotrophoblast layer development
transcription, DNA-templated
regulation of transcription, DNA-templated
hemopoiesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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