Immunogen sequence: SESGDRLDPTA VNILQQIIEL GAETHDATAL ASVVAMAPGT VTVVKQVTEE EPSSNHTVMI QETVQQASVE LAEQHHLVVS SDDVEGIETV TVYTQGGEAS EFIVYVQE
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 94%.
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Protein Aliases: AITD3; ZFAT1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; Zinc finger protein 406; Zinc finger protein ZFAT; zinc-finger gene in AITD susceptibility region; ZNF406
Gene Aliases: AITD3; KIAA1485; ZFAT; ZFAT1; ZNF406
UniProt ID: (Human) Q9P243
Entrez Gene ID: (Human) 57623