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Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coiled-coil domain containing 131; Coiled-coil domain-containing protein 131; MGC23401; proline/serine-rich coiled-coil 2; Proline/serine-rich coiled-coil protein 2; Zinc finger C3H1 domain-containing protein; zinc finger, C3H1-type containing
Gene Aliases: BC033596; CCDC131; CSRC2; KIAA0546; PSRC2; ZFC3H1
UniProt ID: (Human) O60293
Entrez Gene ID: (Human) 196441, (Mouse) 216345
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