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Proteintech

ZFP36L1 Polyclonal Antibody

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View all (15) ZFP36L1 antibodies
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Datasheet
Protocols
Questions & Answers
Tech Support

Product Details

12306-1-AP

Applications Tested Dilution Publications

Western Blot (WB)

 1:500-1:1,000 -

Immunohistochemistry (Paraffin) (IHC (P))

 1:20-1:200 -

Immunocytochemistry (ICC/IF)

 1:20-1:200 View 1 publication 1 publication
Product Specifications

Species Reactivity

 Human, Mouse, Rat

Published species

 Human

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

ZFP36L1 Fusion Protein Ag2952 (1-338 aa encoded by BC018340)
View immunogen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 0.25 mg/mL

Purification

 Antigen affinity chromatography

Storage buffer

 PBS, pH 7.3, with 50% glycerol

Contains

 0.02% sodium azide

Storage conditions

 -20°C

Product Specific Information

Immunogen sequence: MTTTLVSAT IFDLSEVLCK GNKMLNYSAP SAGGCLLDRK AVGTPAGGGF PRRHSVTLPS SKFHQNQLLS SLKGEPAPAL SSRDSRFRDR SFSEGGERLL PTQKQPGGGQ VNSSRYKTEL CRPFEENGAC KYGDKCQFAH GIHELRSLTR HPKYKTELCR TFHTIGFCPY GPRCHFIHNA EERRALAGAR DLSADRPRLQ HSFSFAGFPS AAATAAATGL LDSPTSITPP PILSADDLLG SPTLPDGTNN PFAFSSQELA SLFAPSMGLP GGGSPTTFLF RPMSESPHMF DSPPSPQDSL SDQEGYLSSS SSSHSGSDSP TLDNSRRLPI FSRLSISDD (1-338 aa encoded by BC018340 )

Target Information

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Butyrate response factor 1; early response factor Berg36; EGF-inducible protein CMG1; EGF-response factor 1; ERF-1; mRNA decay activator protein ZFP36L1; TPA-induced sequence 11b; ZFP36 ring finger protein-like 1; ZFP36-like 1; zinc finger protein 36, C3H type-like 1; Zinc finger protein 36, C3H1 type-like 1; zinc finger protein, C3H type, 36-like 1

Gene Aliases: AW742437; AW743212; BERG36; BRF1; Cmg1; D530020L18Rik; ERF-1; ERF1; RNF162B; TIS11B; ZFP36L1

UniProt ID: (Human) Q07352, (Rat) P17431, (Mouse) P23950

Entrez Gene ID: (Human) 677, (Rat) 29344, (Mouse) 12192

Molecular Function: RNA metabolism protein

Function(s)
MAPK cascade nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay vasculogenesis proepicardium development regulation of transcription, DNA-templated apoptotic process heart development cell proliferation response to wounding regulation of gene expression regulation of keratinocyte proliferation phosphatidylinositol 3-kinase signaling neural tube development nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of mRNA 3'-end processing cellular response to insulin stimulus T cell differentiation in thymus multicellular organism growth p38MAPK cascade regulation of mRNA stability protein kinase B signaling cellular response to fibroblast growth factor stimulus positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation positive regulation of monocyte differentiation regulation of myoblast differentiation mesendoderm development mRNA transport chorio-allantoic fusion spongiotrophoblast layer development 3'-UTR-mediated mRNA destabilization ERK1 and ERK2 cascade cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to peptide hormone stimulus cellular response to glucocorticoid stimulus cellular response to hypoxia cellular response to salt stress cellular response to transforming growth factor beta stimulus regulation of stem cell proliferation cellular response to raffinose positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay regulation of keratinocyte apoptotic process positive regulation of intracellular mRNA localization cellular response to phorbol 13-acetate 12-myristate mRNA catabolic process regulation of translation embryonic organ development
Process(es)
DNA binding transcription factor activity, sequence-specific DNA binding mRNA binding mRNA 3'-UTR binding protein binding mRNA 3'-UTR AU-rich region binding poly(A) RNA binding metal ion binding 14-3-3 protein binding AU-rich element binding
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