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ZFYVE27 Antibody (PA5-90842) in WB
Western blot analysis of ZFYVE27 in extracts of rat eye. Samples were incubated with ZFYVE27 Polyclonal antibody (Product # PA5-90842) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
Product Details
PA5-90842
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 217-411 of human ZFYVE27
Conjugate
Unconjugated
Form
liquid
Concentration
1.22 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2806259
Product Specific Information
Immunogen sequence: VEFFRVVSEY RASLQQRMNP KQEEHAFESP PPPDVGGKDG LMDSTPALTP TEDLTPGSVE EAEEAEPDEE FKDAIEETHL VVLEDDEGAP CPAEDELALQ DNGFLSKNEV LRSKVSRLTE RLRKRYPTNN FGNCTGCSAT FSVLKKRRSC SNCGNSFCSR CCSFKVPKSS MGATAPEAQR ETVFVCASCN QTLSK; Positive Samples: Rat eye; Cellular Location: Cell membrane, Cell projection, Endoplasmic reticulum membrane, Multi-pass membrane protein, Recycling endosome membrane, growth cone membrane
Target Information
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protrudin; RP11-459F3.2; Spastic paraplegia 33 protein; zinc finger FYVE domain containing 27; Zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27
Gene Aliases: PROTRUDIN; SPG33; ZFYVE27
UniProt ID: (Human) Q5T4F4, (Rat) Q6P7B7
Entrez Gene ID: (Human) 118813, (Rat) 309376
Molecular Function:
membrane traffic protein
membrane trafficking regulatory protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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