Immunogen sequence: ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNREL
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hLst2; Lateral signaling target protein 2 homolog; Zinc finger FYVE domain-containing protein 28; zinc finger, FYVE domain containing 28
Gene Aliases: KIAA1643; LST2; LYST2; ZFYVE28
UniProt ID: (Human) Q9HCC9
Entrez Gene ID: (Human) 57732
Molecular Function: membrane traffic protein