This target displays homology in the following species: Cow: 86%; Guinea Pig: 83%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 83%
This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.
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Protein Aliases: triple homeobox 1; Triple homeobox protein 1; Zinc finger and homeodomain protein 3; Zinc fingers and homeoboxes protein 3
Gene Aliases: 1810059C13Rik; 4932418O04Rik; 9530010N21Rik; Kiaa0395; mKIAA0395; Tix1; Zhx3
UniProt ID: (Mouse) Q8C0Q2
Entrez Gene ID: (Mouse) 320799
Molecular Function:
helix-turn-helix transcription factor
homeobox transcription factor
nucleic acid binding
transcription factor
zinc finger transcription factor
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