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Proteintech
ZIC1 Polyclonal Antibody
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Product Details
25004-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZIC1 fusion protein Ag13400
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: DFLFRNRGFG DAAAAASAQH SLFAASAGGF GGPHGHTDAA GHLLFPGLHE QAAGHASPNV VNGQMRLGFS GDMYPRPEQY GQVTSPRSEH YAAPQLHGYG PMNVNMAAHH GAGAFFRYMR QPIKQELICK WIEPEQLANP KKSCNKTFST MHELVTHVTV EHVGGPEQSN HICFWEECPR EGKPFKAKYK LVNHIRVHTG EKPFPCPFPG CGKVFARSEN LKIHKRTHTG EKPFKCEFEG CDRRFANSSD RKKHMHVHTS DKPYLCKMCD KSYTHPSSLR KHMKVHESSS QGSQPSPAAS SGYESSTPPT IVSPSTDNPT TSSLSPSSSA VHHTAGHSAL SSNFNEWYV
Target Information
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1
Gene Aliases: CRS6; ZIC; ZIC1; ZNF201
UniProt ID: (Human) Q15915
Entrez Gene ID: (Human) 7545, (Rat) 64618
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
molecular_function
nucleic acid binding
C2H2 zinc finger transcription factor
transcription from RNA polymerase II promoter
pattern specification process
brain development
adult walking behavior
regulation of smoothened signaling pathway
spinal cord development
cell differentiation
positive regulation of protein import into nucleus
inner ear morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
central nervous system development
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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