|Tested species reactivity||Bovine, Dog, Chicken, Horse, Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (370 CDRRFANSSDRKKHMH 385) of ZIC2 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||4-7 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects. Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.